Research articles
Longer reads on how specific peptides work, how stable they are, and what the evidence does and does not show.
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PT-141 (Bremelanotide) and Melanocortin Receptor Signaling: MC4R Activation, Sexual Motivation Pathways, and FDA Approval Evidence
Signaling
PT-141 (bremelanotide; Vyleesi®) is a cyclic heptapeptide melanocortin receptor agonist that activates MC1R, MC3R, and MC4R receptors in the central nervous sys
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Kisspeptin and GPR54/KISS1R Signaling: Hypothalamic Control of the GnRH Pulse Generator and Reproductive Endocrine Axis
Signaling
Kisspeptin is a family of hypothalamic neuropeptides (kisspeptin-54, -14, -13, -10) encoded by the KISS1 gene and processed from a 145-amino acid precursor. All